Moving up but Not Moving Ahead -

Right Nutrition for Deviations!

Linear growth in early childhood is a strong marker of healthy growth and is also closely linked with child development in several domains including cognitive, language and sensory-motor capacities. Stunting indicates linear growth retardation that has been estimated to affect >30% of children aged <5 years of age.1 Children are defined as stunted if their height-for-age is more than two standard deviations below the WHO Child Growth Standards median.  

Stunting is a result of chronic or recurrent undernutrition, usually associated with poor health and nutrition, frequent illness and/or inappropriate feeding and care in early childhood.2 The major causes of stunting (linear growth retardation) are3,4:

  • Recurrent infections 

  • Poor nutrient intake, absorption or utilization 

  • Micronutrient deficiencies 

  • Biological factors: Fetal growth restriction; maternal height 

 
Cognitive Function in Early Childhood

The preschool and school years are periods during which considerable learning occurs and higher cognitive functioning and skills needed for success emerge. It is a time of rapid and dramatic changes in the brain plasticity, and of fundamental acquisition of cognitive development and interpersonal skills. Both the learning environment and nutrition (including availability of protein, essential fatty acids, and micronutrients) during early childhood can influence brain functions such as neurogenesis, migration, cell division, myelination, and synaptic development and thus influence later intellectual and mental health outcomes.1

 
Outcomes Associated with Underweight and Stunting1: 
  1. Delays in cognitive ability
  2. Poorer attention
  3. Poorer social relationships at school age
 
 Importance of Adequate Nutrition During Catch-up Growth5-9
  • Better nutritional and therapeutic regimens provide effective and safer catch-up growth in children with malnutrition and growth abnormalities 

  • Attained height is the result of the interaction between genetic endowment and nutrient availability during the growth period 

  • Both macronutrients and micronutrients help in the formation of “building blocks” for growth 

  • Arginine promotes the multiplication of cells and help bones grow longer and increases height by +0.33cm in a year 

  • Evidence indicates that catch-up growth can be achieved despite of stunted growth in infancy 

  • A meta-analysis including 29814 children from 20 developing countries suggested that nutritional supplementation could improve children’s cognitive development 

 

Approximately 40% to 60% of adult bone mass is accrued during the adolescent years, with 25% of peak bone mass acquired during the 2-year period around peak height velocity.10 Hence, nutritional supplements have been recognized as the most suitable method of improving growth and physical health of children in developing countries. They are also crucial for early development including cognition.9 Thus, intervention at an early age is required to prevent irreversible changes during growth of child, by improving the intake of growth-limiting nutrients, including administration of micronutrient supplements, fortification of food with micronutrients or improved dietary intake. 

RELATED CONTENT

References:

  1. Nguyen PH, Tran LM, Khuong LQ, Young MF, Duong TH, Nguyen HC, DiGirolamo AM, Martorell R, Ramakrishnan U. Child Linear Growth During and After the First 1000 Days Is Positively Associated with Intellectual Functioning and Mental Health in School-Age Children in Vietnam. J Nutr. 2021 Sep 4;151(9):2816-2824. doi: 10.1093/jn/nxab182. PMID: 34113979; PMCID: PMC8417934.
  2. https://www.who.int/health-topics/malnutrition accessed on 9.05.2022
  3. https://www.who.int/teams/nutrition-and-food-safety/monitoring-nutritional-status-and-food-safety-and-events/healthy-growth-and-development#:~:text=The%20most%20direct%20causes%20of,other%20forms%20of%20nutrient%20loss accessed on 1.27.2025
  4. Victora CG, Villar J, Barros FC, Ismail LC, Chumlea C, Papageorghiou AT, Bertino E, Ohuma EO, Lambert A, Carvalho M, Jaffer YA, Altman DG, Noble JA, Gravett MG, Purwar M, Frederick IO, Pang R, Bhutta ZA, Kennedy SH; International Fetal and Newborn Growth Consortium for the 21st Century (INTERGROWTH-21st). Anthropometric Characterization of Impaired Fetal Growth: Risk Factors for and Prognosis of Newborns With Stunting or Wasting. JAMA Pediatr. 2015 Jul;169(7):e151431.
  5. Gat-Yablonski G, Phillip M. Nutritionally-induced catch-up growth. Nutrients. 2015 Jan 14;7(1):517-51.
  6. van Vught AJ, Dagnelie PC, Arts IC, Froberg K, Andersen LB, El-Naaman B, Bugge A, Nielsen BM, Heitman BL. Dietary arginine and linear growth: the copenhagen School child intervention study. British journal of nutrition. 2013 Mar;109(6):1031-9.
  7. Crookston BT, Schott W, Cueto S, et al. Postinfancy growth, schooling, and cognitive achievement: young lives. Am J Clin Nutr 2013; 98: 1555–63.
  8. Hennessy Á, Browne F, Kiely M, Walton J, Flynn A. The role of fortified foods and nutritional supplements in increasing vitamin D intake in Irish preschool children. Eur J Nutr. 2017;56(3):1219-1231.
  9. Impact of nutritional supplements on cognitive development of children in developing countries: A meta-analysis. Sci Rep. 2017;7(1):1-9.
  10. Golden NH, Abrams SA; Committee on Nutrition. Optimizing bone health in children and adolescents. Pediatrics. 2014 Oct;134(4):e1229-43.

 

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